Shore mtc

From SHORE wiki
Revision as of 14:32, 23 September 2011 by Felo80 (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

The subprogram shore mtc implements various multiple testing correction methods. The expected input is a tab-delimited text file with a header, and the column containing the p-values to be adjusted must be named raw_p.

Implemented methods include

  • Benjamini-Hochberg false discovery rate control (fdr_bh)
  • Bonferroni familywise error rate control (fwer_bonferroni)
  • Holm familywise error rate control (fwer_holm)
  • Hochberg familywise error rate control (fwer_hochberg)
  • Sidak singlestep familywise error rate control (fwer_sidak_ss)
  • Sidak stepdown familywise error rate control (fwer_sidak_sd)
  • Benjamini-Yekutieli false discovery rate control (fdr_by).


Usage: shore mtc [OPTIONS]

Mandatory
-m, --method=<arg[,...]> Select correction method(s), out of: fdr_bh, fwer_bonferroni, fwer_holm, fwer_hochberg, fwer_sidak_ss, fwer_sidak_sd, fdr_by
-i, --input-file=<arg> (Default: stdin) The file the raw p-values are read from (expects a column 'raw_p')
-o, --output-file=<arg> (Default: stdout) Output file
Output
-u, --fdr-max=<arg> (Default: 1) Maximum q-value to report
-e, --echo-comments Echo all comments read from input files to stdout
-q, --quiet Do not print input, only report the q-values
Other
-j, --input-header=<arg[,...]> Use arg as input file header